Dr Gabor Somlyai on Deuterium’s Effect on Cancer, Insulin Resistance

Company Overview

• Established in 1993
• Registered the first anticancer drug for veterinary use in 1993
• Developed a deuterium-​​depleted product called Preventa
• Received investments of $0.4 million in 2005 and $1.3 million in 2012
• Generated over $10 million to finance research

Deuterium and Living Organisms

• Deuterium is a heavy isotope of hydrogen
• Deuterium concentration in the body is six times higher than calcium
• Deuterium’s role in living organisms has not been extensively investigated

Deuterium-​​Depleted Water Experiments

• First paper published in 1993 showed that deuterium can modify cell growth rate
• Recent experiments confirmed that lower deuterium concentration results in lower cell growth rate
• Cells are sensitive to even a 1 ppm decrease in deuterium concentration

Deuterium and Cancer Cells

• Damaged mitochondria in cancer cells are unable to produce deuterium-​​depleted metabolic water
• Lowering deuterium concentration can trigger apoptosis and cyanoprosis in cancer cells

Deuterium-​​Depleted Water and Cancer Prevention

• Long-​​term study showed that consuming deuterium-​​depleted water can prevent cancer appearance in mice
• Registered anticancer drug for pets, with 50% of dogs and cats cured by replacing normal water with deuterium-​​depleted water

Clinical Trials and Patient Results

• Phase 2 clinical trial with prostate cancer patients showed 80% decrease in tumor marker value and 160 cubic centimeter decrease in prostate volume

• Survival study of 304 lung cancer patients consuming deuterium-​​depleted water showed a median survival time of 48 months, a six-​​fold increase compared to standard treatment # Deuterium Depleted Water (DW) and Health

• 204 cancer patients studied, tumor-​​free when starting DW therapy

  • Cumulative follow-​​up time over 1000 years
  • Average time between diagnosis and starting DW therapy: 300 days
  • Length of DW consumption: 500 days
• 13 patients lost during follow-up 
  • 2 deaths not related to cancer
  • 3 relapsed during DW treatment
  • 8 died years after stopping DW
• Results suggest DW therapy can almost 100% prevent cancer relapse

DW and Diabetes

• Rats study: diabetic rats tested with different DW concentrations 
  • Best results with 125–140 ppm
  • Lower concentrations significantly reduced blood sugar levels
• Glute 4 protein responsible for glucose uptake from vessels 
  • Lower DW concentrations stimulate insulin signal transduction
  • Cells can pick up glucose from vessels more efficiently

Human Clinical Trial

• 30 patients consumed 105 ppm DW for 90 days 
  • Fasting glucose levels decreased
  • 11 patients (30%) showed reduced insulin resistance
• Preclinical investigation and clinical trial results support DW’s potential in reducing blood sugar levels and improving glucose disposal

Conclusion

• Heavy hydrogen (deuterium) presence in metabolism cannot be ignored
• Life influenced by food and water consumed, determining deuterium ratio
• Proper cellular function relies on deuterium ratio
• Products available for prevention, veterinary use, and clinical research
• Future phase 2 clinical trials planned