• Contents
  • Key Takeaways
  • Protocols
  • Source
  • Full Notes
  • Support the Podcast
Last Updated: 12.06.23

Dr. Andy Galpin: Optimal Protocols to Build Strength & Grow Muscles

Dr. Huberman hosts Episode 2 of the 6‑part series featuring Dr. Galpin, discussing optimal protocols for strength, hypertrophy, speed, and power. They explore training principles, mechanisms, and various topics like repetitions, rest periods, warm-​​ups, nutrition, and exercises for specific goals.

Key Takeaways

High level takeaways from the episode.

Ability to stand, move, and catch oneself from a fall is a function of muscle power. Strength training is essential for maintaining high-​​quality muscle and functionality.

Strength training keeps the nervous system healthy and young. It is essential for overall health, longevity, and quality of life.

Resistance-​​type movements and continuation of movement throughout the lifespan keep the brain young and healthy.

Load-​​bearing exercise stimulates bones to release osteocalcin

  • Osteocalcin acts as a hormone, travels to the brain, enhances memory systems and neuron health

No need to adjust strength training around menstrual cycle

  • Evidence shows strength won’t change during different phases of the cycle

Carbohydrates can add fuel for muscle protein synthesis process

  • Additive benefits when combined with protein and strength training

Endurance training can inhibit mTOR, leading to the “interference effect” on hypertrophy.

Nine adaptations for training:

  • Skill and technique
  • Speed
  • Power (speed x force)
  • Strength
  • Hypertrophy
  • Muscular endurance
  • Anaerobic capacity
  • Maximal aerobic capacity
  • Long duration steady-​​state exercise

Both linear periodization (focusing on just strength for 6–8 weeks) or undulating periodization (e.g., Monday — power, Wednesday — strength, Friday — hypertrophy) are equally effective.

Volume is the primary driver for hypertrophy. Intensity is the primary driver for speed, power, and strength.

Warm-​​up should be as long as needed to feel ready and activated. Preserve intensity and volume.

For power and strength, allow time to learn and adapt to exercises before making changes. Stick with the same exercises for 6–12 weeks before making adjustments.

Repetition range for power: 30% to 70% of one repetition max. Attempt to go fast for maximum power development.

Examples of exercises for power development:

  • Plyometrics
  • Medicine ball throws
  • Short sprints
  • Air bike sprints
  • Weightlifting movements (snatches and clean and jerks)
  • Clapping push-​​ups
  • Speed squats
  • Kettlebell swings

Examples of exercises for strength development:

  • Pushes and pulls
  • Carries (farmer’s carry, sled push, sled drag, yoke walk)
  • Eccentric overload training (advanced technique, use caution)
  • Cluster sets (mini breaks between repetitions)

Factors affecting hypertrophy: intensity, intent, sleep, nutrition, stress. Breaking through plateaus: change intensity or volume, try different exercises or rep ranges.

Gymnastics, ball sports, skateboarding, and martial arts all have unique benefits

  • Encourage children to participate in a variety of sports for well-​​rounded development
  • Early exposure to different activities can help with muscle activation and overall athleticism later in life

Restricting workouts to 50–60 minutes, 3–4 times a week can help prevent fatigue.

Protocols

Science-​​based tools and supplements that push the needle.

Training for Strength

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Training for Power

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Training for Hypertrophy

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Eccentric Overload Training

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Cluster Sets

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Stretching and Fatigue Management

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Prilepin’s Chart

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Breathing During Repetitions & Sets

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Rep Cadence for Strength & Hypertrophy

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Source

We recommend using this distillation as a supplemental resource to the source material.

  • Dr. Andy Galpin: Optimal Protocols to Build Strength & Grow Muscles

    Huberman Lab #110

    Dr. Huberman hosts Episode 2 of the 6‑part series with Dr. Galpin, discussing optimal protocols for strength, hypertrophy, speed, and power, covering training principles, mechanisms, and various topics.

Full Notes

Support the Podcast